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Lower Limb Reduction Defects

Lower limb reduction defects occur when a part of or the entire leg (lower limb) of a fetus fails to form completely during pregnancy. The defect is referred to as a “limb reduction” because a limb is reduced from its normal size or is missing.

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This effort is supported by funding from the U.S. Centers for Disease Control and Prevention Environmental Public Health Tracking Program, Cooperative Agreement Number 5U38EH000619-02. The contents of this Website are solely the responsibility of the authors and do not necessarily represent the official views of the Centers for Disease Control and Prevention.